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IFN-gamma R1

Brief Information

Name:Interferon gamma receptor
Target Synonym:
Number of Launched Drugs:11
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Approved

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
IF1-H5223 Human Human IFN-gamma R1 / IFNGR1 Protein, His Tag
IF1-H5223-structure
IF1-H5223-sds
IF1-H5254 Human Human IFN-gamma R1 / IFNGR1 Protein, Fc Tag
IF1-H5254-structure
IF1-H5254-sds
ACRO Quality

Part of Bioactivity data

IF1-H5254-ELISA
 IFN-gamma R1 ELISA

Immobilized Human IFN-gamma, premium grade (Cat. No. IFG-H4211) at 5 μg/mL (100 μL/well) can bind Human IFN-gamma R1, Fc Tag (Cat. No. IF1-H5254) with a linear range of 0.1-6 ng/mL (QC tested).

IF1-H5223-ELISA
 IFN-gamma R1 ELISA

Immobilized Human IFN-gamma, premium grade (Cat. No. IFG-H4211) at 5 μg/mL (100 μL/well) can bind Human IFN-gamma R1, His Tag (Cat. No. IF1-H5223) with a linear range of 0.01-0.313 μg/mL (Routinely tested).

Synonym Name

IFNGR1,CD119,CDw119,IFNGR,IFN-gamma-R1

Background

Interferon gamma receptor 1 (IFNGR1) is also known as CD antigen CD119, which belongs to the type II cytokine receptor family. IFNGR1 contains two fibronectin type-III domains and two Ig-like C2-type (immunoglobulin-like) domains. IFNGR1 / CD119 is receptor for interferon gamma. Two receptors bind one interferon gamma (IFNG) dimer.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Interferon gamma biosimilar (Livzon Pharmaceutical Group) Approved Livzon Pharmaceutical Group Inc Mainland China Arthritis, Rheumatoid Livzon Pharmaceutical Group Inc 1998-01-01 Arthritis, Rheumatoid Details
Interferon gamma (Hayashibara) OH-6000 Approved Hayashibara Ogamma Japan Skin Neoplasms null 1997-08-05 Skin Neoplasms Details
Recombinant interferon gamma (Shanghai Chemo Wanbang Biopharma) Approved Shanghai Chemo Wanbang Biophama Co Ltd 伽玛, gamma Mainland China Arthritis, Rheumatoid; Liver Cirrhosis Shanghai Chemo Wanbang Biophama Co Ltd 1998-01-01 Arthritis, Rheumatoid; Liver Cirrhosis; Granulomatous Disease, Chronic Details
Interferon gamma-1a biosimilar (Shionogi) S-6810 Approved Shionogi & Co Ltd Imunomax-γ Japan Mycosis Fungoides; Carcinoma, Renal Cell; Myocardial Infarction; Communicable Diseases Shionogi & Co Ltd 1989-09-29 Carcinoma, Renal Cell; Myocardial Infarction; Communicable Diseases; Mycosis Fungoides Details
Interferon gamma-1b DasKloster-1001; DasKloster-1001-01 Approved Genentech Inc Immukin, Imukin 1, Actimmune United States Osteopetrosis; Granulomatous Disease, Chronic Horizon Therapeutics Ireland Dac 1999-02-25 Candidemia; Macular Degeneration; Hepatitis C, Chronic; Mycobacterium avium-intracellulare Infection; Melanoma; Adenocarcinoma, Mucinous; Uveitis; Retinal Degeneration; Granulomatous Disease, Chronic; Uveitis, Anterior; Tuberculosis, Pulmonary; Psoriasis; Pulmonary Aspergillosis; Osteopetrosis; Aspergillosis; Respiratory Tract Infections; Retinal Diseases; Lung Diseases; Pulmonary Fibrosis; Friedreich Ataxia; Colonic Neoplasms; Fibrosis; Liver Cirrhosis; Idiopathic Pulmonary Fibrosis; Rectal Neoplasms; Eye Diseases, Hereditary; Pneumonia; HIV Infections; Cystic Fibrosis Details
Interferon biosimilar (LG Life Sciences) Approved Lg Life Sciences Ltd Leukemia Lg Life Sciences Ltd 1989-01-01 Leukemia Details
Interferon gamma-1a (Asubio Pharma) SUN-4800 Approved Asubio Biogamma Japan Mycosis Fungoides Asubio 1992-01-01 Mycosis Fungoides Details
Interferon gamma biosimilar (Pharmaclon) Approved Pharmaclon Ingaron Russian Federation Chlamydia Infections; Tuberculosis, Pulmonary; Influenza, Human; HIV Infections; Hepatitis B; Herpes Zoster; Warts; Hepatitis C; Neoplasms; Respiratory Distress Syndrome, Newborn; Prostatitis Pharmaclon 2011-01-01 HIV Infections; RNA Virus Infections; Warts; Papillomavirus Infections; Neoplasms; Tuberculosis, Pulmonary; Chlamydia Infections; Influenza, Human; Hepatitis B; Hepatitis C; Prostatitis; Lentivirus Infections; Condylomata Acuminata; Herpes Zoster; Respiratory Distress Syndrome, Newborn Details
Interferon Gamma (Materia Medica Holding) Approved Materia Medica Holding Research And Production Company Anaferon Virus Diseases; Bacterial Infections Details
Interferon gamma biosimilar (Center for Genetic Engineering and Biotechnology) Approved Center For Genetic Engineering And Biotechnology Idiopathic Pulmonary Fibrosis; Tuberculosis Details
Interferon gamma biosimilar (Recpharma) Approved Recpharma IMMUNEX Osteoporosis; Virus Diseases; Neoplasms; Granulomatous Disease, Chronic Details
Interferon gamma biosimilar (Livzon Pharmaceutical Group) Approved Livzon Pharmaceutical Group Inc Mainland China Arthritis, Rheumatoid Livzon Pharmaceutical Group Inc 1998-01-01 Arthritis, Rheumatoid Details
Interferon gamma (Hayashibara) OH-6000 Approved Hayashibara Ogamma Japan Skin Neoplasms null 1997-08-05 Skin Neoplasms Details
Recombinant interferon gamma (Shanghai Chemo Wanbang Biopharma) Approved Shanghai Chemo Wanbang Biophama Co Ltd 伽玛, gamma Mainland China Arthritis, Rheumatoid; Liver Cirrhosis Shanghai Chemo Wanbang Biophama Co Ltd 1998-01-01 Arthritis, Rheumatoid; Liver Cirrhosis; Granulomatous Disease, Chronic Details
Interferon gamma-1a biosimilar (Shionogi) S-6810 Approved Shionogi & Co Ltd Imunomax-γ Japan Mycosis Fungoides; Carcinoma, Renal Cell; Myocardial Infarction; Communicable Diseases Shionogi & Co Ltd 1989-09-29 Carcinoma, Renal Cell; Myocardial Infarction; Communicable Diseases; Mycosis Fungoides Details
Interferon gamma-1b DasKloster-1001; DasKloster-1001-01 Approved Genentech Inc Immukin, Imukin 1, Actimmune United States Osteopetrosis; Granulomatous Disease, Chronic Horizon Therapeutics Ireland Dac 1999-02-25 Candidemia; Macular Degeneration; Hepatitis C, Chronic; Mycobacterium avium-intracellulare Infection; Melanoma; Adenocarcinoma, Mucinous; Uveitis; Retinal Degeneration; Granulomatous Disease, Chronic; Uveitis, Anterior; Tuberculosis, Pulmonary; Psoriasis; Pulmonary Aspergillosis; Osteopetrosis; Aspergillosis; Respiratory Tract Infections; Retinal Diseases; Lung Diseases; Pulmonary Fibrosis; Friedreich Ataxia; Colonic Neoplasms; Fibrosis; Liver Cirrhosis; Idiopathic Pulmonary Fibrosis; Rectal Neoplasms; Eye Diseases, Hereditary; Pneumonia; HIV Infections; Cystic Fibrosis Details
Interferon biosimilar (LG Life Sciences) Approved Lg Life Sciences Ltd Leukemia Lg Life Sciences Ltd 1989-01-01 Leukemia Details
Interferon gamma-1a (Asubio Pharma) SUN-4800 Approved Asubio Biogamma Japan Mycosis Fungoides Asubio 1992-01-01 Mycosis Fungoides Details
Interferon gamma biosimilar (Pharmaclon) Approved Pharmaclon Ingaron Russian Federation Chlamydia Infections; Tuberculosis, Pulmonary; Influenza, Human; HIV Infections; Hepatitis B; Herpes Zoster; Warts; Hepatitis C; Neoplasms; Respiratory Distress Syndrome, Newborn; Prostatitis Pharmaclon 2011-01-01 HIV Infections; RNA Virus Infections; Warts; Papillomavirus Infections; Neoplasms; Tuberculosis, Pulmonary; Chlamydia Infections; Influenza, Human; Hepatitis B; Hepatitis C; Prostatitis; Lentivirus Infections; Condylomata Acuminata; Herpes Zoster; Respiratory Distress Syndrome, Newborn Details
Interferon Gamma (Materia Medica Holding) Approved Materia Medica Holding Research And Production Company Anaferon Virus Diseases; Bacterial Infections Details
Interferon gamma biosimilar (Center for Genetic Engineering and Biotechnology) Approved Center For Genetic Engineering And Biotechnology Idiopathic Pulmonary Fibrosis; Tuberculosis Details
Interferon gamma biosimilar (Recpharma) Approved Recpharma IMMUNEX Osteoporosis; Virus Diseases; Neoplasms; Granulomatous Disease, Chronic Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
rSIFN-co Phase 3 Clinical Sichuan Huiyang Life Science and Technology Corp Carcinoma, Renal Cell; Hepatitis B, Chronic; Colonic Neoplasms; Coronavirus Disease 2019 (COVID-19); Neuroendocrine Tumors; Prostatic Neoplasms; Coronaviridae Infections; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma; Carcinoma, Hepatocellular Details
Interferon gamma (aerosol, IPF/ COPD), Stony Brook University School of Medicine Phase 2 Clinical Nostrum, Stony Brook University School Of Medicine, Nyu Langone Medical Center Pulmonary Disease, Chronic Obstructive Details
rSIFN-co Phase 3 Clinical Sichuan Huiyang Life Science and Technology Corp Carcinoma, Renal Cell; Hepatitis B, Chronic; Colonic Neoplasms; Coronavirus Disease 2019 (COVID-19); Neuroendocrine Tumors; Prostatic Neoplasms; Coronaviridae Infections; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma; Carcinoma, Hepatocellular Details
Interferon gamma (aerosol, IPF/ COPD), Stony Brook University School of Medicine Phase 2 Clinical Nostrum, Stony Brook University School Of Medicine, Nyu Langone Medical Center Pulmonary Disease, Chronic Obstructive Details

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